Job Description

The Immunology department at MD Anderson Cancer Center seeks to determine the fundamental cellular and molecular mechanisms of a wide range of processes by which the body recognizes and eliminates pathogens and uses these findings to unleash the patient's immune system against previously treatment-resistant cancers. The therapeutics developed treat the immune system rather than the cancer itself and are applicable to many cancers. The role of immunological and epigenetic pathways in resistance and response to immune checkpoint therapy.

General Laboratory duties or procedures:
1. To work with animal and human samples (Handling, Treatments, Inoculation, and Processing of samples for long-term storage)
2. Perform single-cell RNA sequencing, able to run the data in different packages, and analyze the tumor immune micro-environment
3. Perform ATAC-sequencing, able to run the data in different packages, and analyze chromatin accessibility
4. CyTOF staining and analyses of the data
5. Flow cytometry staining and analyses
6. Perform CHIP-sequencing, able to run the data in different packages, and analyze chromatin accessibility
7. Molecular biology techniques like PCR, RNA/DNA isolation, western blot, and knock-in/knock-out using CRISPR technology.

LEARNING OBJECTIVES
1. To understand immunological pathways involved in response and resistance to immune checkpoint therapy at the single-cell level.
2. To understand the epigenetic regulations of immune sub-populations.
3. To analyze the single-cell RNA sequencing and ATAC sequencing data.

ELIGIBILITY REQUIREMENTS
PhD in Immunology, Biochemistry, or Molecular Biology

POSITION INFORMATION
MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition05/02/2025

Job Tags

Full time,

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